Topology
Instruments, deck positions, plate hotels, reachable transfer points, transport arms, and physical hand-off edges.
labspine.ai
LabSpine
The canonical control model for robot-powered biology.
Design a heterogeneous workcell, compile it into real instrument protocols, validate against simulation, and read the logs back when the pipeline breaks.
1 IR
topology + capabilities + process
2 backends
Opentrons today, Hamilton next
4 layers
robot -> hand-off -> LIMS -> bioinformatics
Labs do not fail in one place. A plate can run correctly, disappear at the hand-off, land under the wrong sample ID, and surface later as bad bioinformatics. LabSpine follows the sample through the whole chain.
canonical cell model
One spine, many instruments.
Capabilities
Operation ranges, labware support, heads, consumables, throughput, I/O contracts, and vendor-specific limits.
Process
The assay as a dependency graph with timing constraints, sample identity, labware lifecycle, and resource needs.
validate, repair, diagnose
The agent proposes. The model decides.
LabSpine treats LLMs as proposers, not authorities. Every design becomes a structured patch to the model, then passes through catalog checks, solver constraints, simulation, and human gates.
Assay request
Process DAG
Cell model
Solver + deck layout
Compiler
Opentrons protocol
Validation
Repair loop
Run logs
Break localization
interactive proof path
Where did the sample break?
Live API
Checking connection
diagnostician verdict
Localized to hand-off
Sample S003 completed the cell run but never produced a matching LIMS hand-off event.
Ready
Cell
Robot run completed
Hand-off
No transfer event
LIMS
No accepted record
Bioinformatics
Missing downstream input
JavaScript is disabled, so the scenario buttons cannot switch cases. The table below shows the default silent hand-off drop.
| Sample | Cell | Hand-off | LIMS | Bioinformatics | Landed as |
|---|---|---|---|---|---|
| S001 | OK | OK | OK | OK | S001 |
| S002 | OK | OK | OK | OK | S002 |
| S003 | OK | FAIL | FAIL | FAIL | - |
api findings
Structured failure report
- HANDOFF_SILENT_DROP Waiting for the live diagnostic response.
Run a live scenario to view generated artifacts.labspine.ai
What the site says
LabSpine is a control-plane product for automated labs: one model that supports design, validation, compiler output, and operational diagnostics.
What the demo proves
A thin vertical slice already compiles real Opentrons protocol code, validates it, repairs infeasible designs, and localizes sample failures across the pipeline.